Schistosoma mansoni lncRNAs Database


Schistosoma mansoni single-cell Clusters

This site contains web resources described in the submitted manuscript "Long non-coding RNAs as markers of Schistosoma mansoni single-cell populations" (2022) by David Morales-Vicente, Lu Zhao, Gilbert O. Silveira, Ana C. Tahira, Murilo S. Amaral, James J. Collins III, Sergio Verjovski-Almeida.

Based on a re-analysis of public sc-RNAseq raw data from Wendt, G., Zhao, L., Chen, R., Liu, C., O'donoghue, A.J., Caffrey, C.R., Reese, M.L., and Collins, J.J., 3rd (2020). A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding. Science 369, 1644-1649. doi: 10.1126/science.abb7709 The re-analysis used as reference the lncRNAs transcriptome described by Maciel, L.F., Morales-Vicente, D.A., Silveira, G.O., Ribeiro, R.O., Olberg, G.G.O., Pires, D.S., Amaral, M.S., and Verjovski-Almeida, S. (2019). Weighted gene co-expression analyses point to long non-coding RNA hub genes at different Schistosoma mansoni life-cycle stages. Front. Genet. 10:823. doi: 10.3389/fgene.2019.00823 merged with the S. mansoni genome and transcriptome v7.1 annotation.


Schistosoma mansoni Atlas

This site contains the web resource described in the paper "Atlas of Schistosoma mansoni long non-coding RNAs and their expression correlation to protein-coding genes" (2018) by Elton J. R. Vasconcelos, Vinícius C. Mesel, Lucas F. daSilva, David S. Pires, Guilherme M. Lavezzo, Adriana S. A. Pereira, Murilo S. Amaral and Sergio Verjovski-Almeida, Database, Volume 2018: bay068, https://doi.org/10.1093/database/bay068.

Based on data from Vasconcelos, EJR et al., The Schistosoma mansoni genome encodes thousands of long noncoding RNAs predicted to be functional at different parasite life-cycle stages. Scientific Reports 7: 10508, 2017.