Schistosoma mansoni lncRNAs Database


Schistosoma mansoni Single-cell Clusters Atlas

This site contains web resources described in the paper by David A. Morales-Vicente, Lu Zhao, Gilbert O. Silveira, Ana C. Tahira, Murilo S. Amaral, James J. Collins III, Sergio Verjovski-Almeida (2022) Single-cell RNA-seq analyses show that long non-coding RNAs are conspicuously expressed in Schistosoma mansoni gamete and tegument progenitor cell populations. Front. Genet. 13:924877. doi: 10.3389/fgene.2022.924877

Based on a re-analysis of public sc-RNAseq raw data from Wendt, G., Zhao, L., Chen, R., Liu, C., O'donoghue, A.J., Caffrey, C.R., Reese, M.L., and Collins, J.J., 3rd (2020). A single-cell RNA-seq atlas of Schistosoma mansoni identifies a key regulator of blood feeding. Science 369, 1644-1649. doi: 10.1126/science.abb7709 The re-analysis used as reference the lncRNAs transcriptome described by Maciel, L.F., Morales-Vicente, D.A., Silveira, G.O., Ribeiro, R.O., Olberg, G.G.O., Pires, D.S., Amaral, M.S., and Verjovski-Almeida, S. (2019). Weighted gene co-expression analyses point to long non-coding RNA hub genes at different Schistosoma mansoni life-cycle stages. Front. Genet. 10:823. doi: 10.3389/fgene.2019.00823 merged with the S. mansoni genome and transcriptome v7.1 annotation.


Schistosoma mansoni lncRNAs Database

This site contains the web resource described in the paper "Atlas of Schistosoma mansoni long non-coding RNAs and their expression correlation to protein-coding genes" (2018) by Elton J. R. Vasconcelos, Vinícius C. Mesel, Lucas F. daSilva, David S. Pires, Guilherme M. Lavezzo, Adriana S. A. Pereira, Murilo S. Amaral and Sergio Verjovski-Almeida, Database, Volume 2018: bay068, https://doi.org/10.1093/database/bay068.

Based on data from Vasconcelos, EJR et al., The Schistosoma mansoni genome encodes thousands of long noncoding RNAs predicted to be functional at different parasite life-cycle stages. Scientific Reports 7: 10508, 2017.